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CHRONIC DRY EYE

Date: 04/30/24

Dry eye is one the most common eye disorders. It is caused by the eye’s inability to produce tears or aqueous fluid to appropriately lubricate the eye. There are many reasons for decreased tear production including age and medications. See table 1 for a more complete list.

Dry eyes can lead to inflammation and damage to the eye surface. Signs and symptoms of dry eye include eye redness, itching, sensitivity to light, difficulty with nighttime driving, stinging and burning, and watery eyes.1

 

Table 1. Causes of Decreased Tear Production

Age

Medical Conditions:

Sjogren’s Syndrome

Rheumatoid Arthritis

Allergic Eye disease

Scleroderma

Sarcoidosis

Thyroid disorders

Vitamin A deficiency

Parkinson’s disease

Medications:

Antihistamines

Decongestants

Antihypertensives

Hormone replacement therapy

Birth Control

Acne

Corneal nerve de-sensitivity:

Laser eye surgery

Contact lens use

Nerve damage

 

Complications1

Complications can occur due to the decrease in aqueous fluid production and subsequent inflammation:

  • Eye infections, as tears protect the surface of the eye from eye infection
  • Damage to the eye surface due to the constant inflammation leading to abrasion of the corneal surface (and rarely vision loss)
  • A decreased quality of life and difficulty performing everyday tasks such as driving or reading

 

Prevention2

Members can be advised of non-pharmacological aids to help prevent dry eye or improve symptoms. They should avoid air blowing directly in their eyes from hair dryers, car vents, fans, or air conditioners, as examples. Adding a humidifier to increase the moisture in dry environments may help. Wearing sunglasses or protective glasses can help to block the eyes from wind and dry air.

If the member is doing tasks that require long periods of visual concentrations, they should take breaks or blink several times for a few seconds periodically to help distribute the tears evenly over the eyes. If the member smokes, smoking cessation is recommended along withing avoiding smokey areas. Lastly, members should use artificial tears throughout the day to help keep the eyes lubricated.

 

Table 2: Prevention Methods

Avoid air blowing in eyes

Add moisture to air

Wear sunglasses or protective eyewear

Take breaks when doing long tasks

Smoking cessation or avoid smoke

Regular use of artificial tears

 

Treatment1,2

  • Mild dry eyes: Over the counter (OTC) medications can be utilized. Artificial tears are available as solution, ointment, and gel drops. Ointments can be used at nighttime as the patient’s vision will be blurry after administration.
  • Moderate dry eyes: Cyclosporine (Restasis®) and liftegrast (Xiidra®) are available by prescription. The medications help the patient’s eye to produce more tears. Possible adverse effects include burning, stinging, redness, watery eyes, blurry vision, and discharge.3,4
  • In some cases, the patient’s lower eye lid may be too loose. Punctal plugs may be helpful in keeping the tears in the eye.
  • See Table 3 for dry eye product preferred status.

 

Table 3: Meridian’s Preferred Drug List Dry Eye Products

Medication

Preferred Status

Restasis®

Non-Preferred

Xiidra®

Non-preferred

Artificial tear solution

Preferred

Lacrisert

Preferred

Polyvinyl alcohol 1.4%

Preferred

White petrolatum-mineral oil

Preferred

 

References

1.       Dry Eyes. Accessed 4/15/24.

2.       Dry Eye. Accessed /15/24.

3.       Restasis. Accessed 4/17/24.

4.       Xiidra. Accessed 4/17/24.